89-7787-99 Recombinant Human Oncomodulin-1/OCM Protein (His Tag) 50ug PKSH032834
[Elabscience]特徴
- 背景:Oncomodulin-1 (OM) is a small, calcium-binding protein and a macrophage-derived growth factor, which can promote axon regeneration in retinal ganglion cells. Oncomodulin-1 is constitutively secreted by activated macrophages in the vitreous and retina in response to inflammatory conditions that promote optic nerve regeneration. Oncomodulin-1 binds RGCs with high affinity in vitro, but only when cAMP is pharmacologically elevated or if the membrane is permeabilized allowing Oncomodulin-1 access to the cytosolic compartment. Oncomodulin-1 is a member of the superfamily of calmodulin proteins and is a high-affinity calcium ion-binding protein and contains 2 EF-hand domains. OM is found in early embryonic cells in the placenta and also in tumors. It has some calmodulin-like activity with respect to enzyme activation and growth regulation.
仕様
- サイズ:50ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:P0CE72
- タグ種類:N-6His
- アミノ酸配列:Met 1-Ser109
- 遺伝子構造:Recombinant Human Oncomodulin-1 is produced by our E.coli expression system and the target gene encoding Met1-Ser109 is expressed with a 6His tag at the N-terminus.
- 別名(遺伝子名):Oncomodulin-1; OM; Parvalbumin Beta; OCM; OCM1; OCMN
- 分子量:14.3 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 50mM Tris, 100mM NaCl, pH 7.5.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-106537-Elabscience-PKSH032834.pdf
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89-7787-99
Recombinant Human Oncomodulin-1/OCM Protein (His Tag) 50ug
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89-7787-98
Recombinant Human Oncomodulin-1/OCM Protein (His Tag) 10ug
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