89-7787-77 Recombinant Human NgR3/RTN4RL1 Protein (His Tag) 50ug PKSH032820
[Elabscience]特徴
- 背景:Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family. NgR is GPI-anchored and contains eight leucine-rich repeats (LRR), it is the neuronal receptor for the myelin- associated proteins Nogo-A, OMgp (oligodendrocyte myelin glycoprotein), and MAG (myelin-associated glycoprotein) and mediates the inhibition of CNS axonal regeneration both in vitro and in vivo. NgR2 and NgR3 have similar structure and distinct but overlapping expression versus NgR. NgR2 can be metalloproteinase-cleaved to release a soluble ectodomain. NgR2 has also been shown to bind MAG, but ligands for NgR3 have not yet been determined. Mature huaman NgR3 shares 88%, 88%, 48% and 44% amino acid identity with mature mouse NgR3, rat NgR3, human NgRH1 and NgR, repectively.
仕様
- サイズ:50ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:Q86UN2
- タグ種類:C-6His
- アミノ酸配列:Cys25-Ala419
- 遺伝子構造:Recombinant Human Nogo-66 Receptor-related Protein 3/Reticulon-4 Receptor-like 1 is produced by our Mammalian expression system and the target gene encoding Cys25-Ala419 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Reticulon-4 Receptor-Like 1; Nogo Receptor-Like 2; Nogo-66 Receptor Homolog 2; Nogo-66 Receptor-Related Protein 3; NgR3; RTN4RL1; NGRH2; NGRL2
- 分子量:45.5 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Threhalose, pH 7.2.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-106526-Elabscience-PKSH032820.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7787-76
Recombinant Human NgR3/RTN4RL1 Protein (His Tag) 10ug
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89-7787-77
Recombinant Human NgR3/RTN4RL1 Protein (His Tag) 50ug
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