89-7786-53 Recombinant Human MICA Protein (Fc Tag)(Active) 10ug PKSH032753
[Elabscience]
特徴
- 背景：MHC class I polypeptide-related sequence A, also known as MIC-A, PERB11.1 and MICA, is a single-pass type I membrane protein which belongs to the MHC class I family of MIC subfamily. MICA contains one Ig-like C1-type domain and is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells, NKT cells, and most of the subtypes of T cells. MICA is the ligand for NK cell activating receptor KLRK1/NKG2D. MICA seems to have no role in antigen presentation. MICA leads to cell lysis by binding to KLRK1.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q29983
- タグ種類：C-Fc
- アミノ酸配列：Ala23-Glu308
- 遺伝子構造：Recombinant Human MHC Class I Polypeptide-Related Sequence A is produced by our Mammalian expression system and the target gene encoding Ala23-Glu308 is expressed with a Fc tag at the C-terminus.
- 活性：Immobilized Human MICA-Fc at 2μg/ml(100 μl/well) can bind Human NKG2DL2-His(Cat: PKSH032816). The ED50 of Human MICA-Fc is 2.29 ug/ml .
- 別名（遺伝子名）：MHC Class I Polypeptide-Related Sequence A; MIC-A; MICA; PERB11.1
- 分子量：59.9 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106464-Elabscience-PKSH032753.pdf
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89-7786-54
Recombinant Human MICA Protein (Fc Tag)(Active) 50ug
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89-7786-53
Recombinant Human MICA Protein (Fc Tag)(Active) 10ug
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