89-7785-85 Recombinant Human LCP2 Protein (His Tag, N-T7 Tag) 50ug PKSH032716
[Elabscience]
特徴
- 背景：Lymphocyte cytosolic protein 2（LCP2）contains a SAM domain and a SH2 domain. It is highly expressed in spleen, thymus and peripheral blood leukocytes, T-cell and monocytic cell lines, but expressed at lower level in B-cell lines. LCP2 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. It is phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2 during post-translational modification. Studies using LCP2-deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q13094
- タグ種類：C-6His
- アミノ酸配列：Met 1-Pro533
- 遺伝子構造：Recombinant Human Lymphocyte cytosolic protein 2/SH2 Domain-containing Leukocyte Protein of 76 kDa is produced by our E.coli expression system and the target gene encoding Met1-Pro533 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.
- 別名（遺伝子名）：Lymphocyte cytosolic protein 2;SH2 domain-containing leukocyte protein of 76 kDa;SLP-76 tyrosine phosphoprotein;SLP76;LCP2
- 分子量：62.6 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,20% glycerol，pH 8.5.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106429-Elabscience-PKSH032716.pdf
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89-7785-85
Recombinant Human LCP2 Protein (His Tag, N-T7 Tag) 50ug
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89-7785-84
Recombinant Human LCP2 Protein (His Tag, N-T7 Tag) 10ug
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