89-7785-74 ［取扱停止］Recombinant Human LDLR Protein (His Tag/AVI) 10ug PKSH032711
[Elabscience]
特徴
- 背景：Low-density lipoprotein receptor 9 (LDL receptor) is a single-pass type I membrane protein which belongs to the LDLR family. It contains 3 EGF-like domains, 7 LDL-receptor class A domains, and 6 LDL-receptor class B repeats. This protein binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, it functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells. Defects in LDLR will result in familial hypercholesterolemia.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P01130
- タグ種類：C-6His/AVI
- アミノ酸配列：Ala22-Arg788
- 遺伝子構造：Recombinant Human Low-Density Lipoprotein Receptor is produced by our Mammalian expression system and the target gene encoding Ala22-Arg788 is expressed with a AVI, 6His tag at the C-terminus.
- 別名（遺伝子名）：Low-Density Lipoprotein Receptor; LDL Receptor; LDLR;FH;FHC;LDL R;LDL Receptor;LDLCQ2
- 分子量：90.1 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106424-Elabscience-PKSH032711.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7785-75
Recombinant Human LDLR Protein (His Tag/AVI) 50ug
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89-7785-74
Recombinant Human LDLR Protein (His Tag/AVI) 10ug
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