89-7785-59 Recombinant Human CD47/IAP Protein (Fc Tag)(Active) 50ug PKSH032703
[Elabscience]
特徴
- 背景：CD47(Integrin-Associated Protein;IAP) is a 40 - 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages; neutrophils; and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin; and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution; and is reduced in expression on Rh erythrocytes.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q08722
- タグ種類：C-Fc
- アミノ酸配列：Gln19-Pro139
- 遺伝子構造：Recombinant Human Leukocyte Surface Antigen CD47 is produced by our Mammalian expression system and the target gene encoding Gln19-Pro139 is expressed with a Fc tag at the C-terminus.
- 活性：Immobilized Human SIRPA-His(Cat: PKSH033525) at 0.8μg/ml(100 μl/well) can bind Human CD47-Fc. The ED50 of Human CD47-Fc is 0.135 ug/ml .
- 別名（遺伝子名）：Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6
- 分子量：41.9 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB;150mM NaCl;pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106416-Elabscience-PKSH032703.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7785-58
Recombinant Human CD47/IAP Protein (Fc Tag)(Active) 10ug
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89-7785-59
Recombinant Human CD47/IAP Protein (Fc Tag)(Active) 50ug
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