89-7785-28 Recombinant Human Legumain/LGMN Protein (His Tag) 10ug PKSH032687
[Elabscience]特徴
- 背景:Legumain is a lysosomal cysteine protease which is a member of the peptidase C13 family. Though it is found in many tissues, it is highly expressed in the kidney, heart, and placenta. Legumain has a strict specificity for hydrolysis of asparaginyl bonds and can also cleave aspartyl bonds slowly, especially under acidic conditions. Over-expression Legumain in tumors is significant for invasion and metastasis. In addition, Legumain may be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system and negative regulation of neuron apoptosis.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:Q99538
- タグ種類:C-6His
- アミノ酸配列:Ile18-Tyr433
- 遺伝子構造:Recombinant Human Legumain/Asparaginyl Endopeptidase is produced by our Mammalian expression system and the target gene encoding Ile18-Tyr433 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Legumain; Asparaginyl Endopeptidase; Protease Cysteine 1; LGMN; PRSC1
- 分子量:48.7 kDa
- 組成:Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, 10% Glycerol, pH 8.0.
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-106401-Elabscience-PKSH032687.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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89-7785-29
Recombinant Human Legumain/LGMN Protein (His Tag) 50ug
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89-7785-28
Recombinant Human Legumain/LGMN Protein (His Tag) 10ug
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