89-7785-22 Recombinant Human LAMP2/CD107b Protein (His Tag)(Active) 10ug PKSH032684
[Elabscience]
特徴
- 背景：Lysosomal Associated Membrane Protein 2 (LAMP2) is a major component of lysosomal membranes. LAMP2 is a transmembrane glycoprotein about 110kDa. Mature human LAMP2 consists of a 347 amino acid (aa) intralumenal domain, a 24 aa transmembrane segment, and a 35 aa cytoplasmic tail . The lumenal domain is organized into two heavily N-glycosylated regions. Alternate splicing generates a human LAMP2 isoform (LAMP2B) with a substituted juxtamembrane lumenal region, cytoplasmic tail and transmenmbrane segment.LAMP2 itself can cleavage lysosomal luminal domain and degradation lysosomal. In the help of chaperone HSC73,LAMP2 mediates the lysosomal uptake in complex with cargo proteins and is required for the lysosomal destruction of autophagic vacuoles.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P13473
- タグ種類：C-6His
- アミノ酸配列：Leu29-Ile375
- 遺伝子構造：Recombinant Human Lysosome-Associated Membrane Glycoprotein 2 is produced by our Mammalian expression system and the target gene encoding Leu29-Ile375 is expressed with a 6His tag at the C-terminus.
- 活性：Immobilized Human LGALS3(Cat: PKSH032474) at 1.5μg/ml(100 μl/well) can bind Human LAMP2-His. The ED50 of Human LAMP2-His is 12.73 ug/ml .
- 別名（遺伝子名）：Lysosome-Associated Membrane Glycoprotein 2; LAMP-2; Lysosome-Associated Membrane Protein 2; CD107 Antigen-Like Family Member B; CD107b; LAMP2
- 分子量：33.9 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106398-Elabscience-PKSH032684.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7785-23
Recombinant Human LAMP2/CD107b Protein (His Tag)(Active) 50ug
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89-7785-22
Recombinant Human LAMP2/CD107b Protein (His Tag)(Active) 10ug
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