89-7784-53 ［取扱停止］Recombinant Human Interleukin-4/IL-4 Protein (Active) 10ug PKSH032650
[Elabscience]
特徴
- 背景：Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation; survival and gene expression. IL-4 is produced by mast cells; T cells; and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells; characterized by their cytokine-secretion profile that includes secretion of IL-4; IL-5; IL-6; IL-10; and IL-13; which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P05112
- アミノ酸配列：His25-Ser153
- 遺伝子構造：Recombinant Human Interleukin-4 is produced by our E.coli expression system and the target gene encoding His25-Ser153 is expressed.
- 活性：Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 7-27 pg/mL.
- 別名（遺伝子名）：Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4
- 分子量：15.1 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106364-Elabscience-PKSH032650.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
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89-7784-53
Recombinant Human Interleukin-4/IL-4 Protein (Active) 10ug
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89-7784-54
Recombinant Human Interleukin-4/IL-4 Protein (Active) 50ug
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