89-7784-13 Recombinant Human Interleukin-17F/IL-17F Protein (His Tag)(Active) 10ug PKSH032624
[Elabscience]
特徴
- 背景：Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated; but not resting; CD4+ T-cells and activated monocytes. IL-17F has been shown to stimulate the production of several other cytokines; including IL-6; IL-8; and granulocyte colony-stimulating factor. IL-17F can regulate cartilage matrix turnover and stimulates PBMC and T-cell proliferation. IL-17F is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2; TGFB1/TGFB; and monocyte chemoattractant protein-1. Defects in IL-17F are the cause of familial candidiasis type 6 (CANDF6).
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q96PD4
- タグ種類：C-6His
- アミノ酸配列：Arg31-Gln163
- 遺伝子構造：Recombinant Human Interleukin-17F is produced by our Mammalian expression system and the target gene encoding Arg31-Gln163 is expressed with a 6His tag at the C-terminus.
- 活性：Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 21.87 ng/ml.
- 別名（遺伝子名）：Interleukin-17F; IL-17F; Cytokine ML-1; Interleukin-24; IL-24; IL17F; IL24
- 分子量：16.0 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB;150mM NaCl;pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106344-Elabscience-PKSH032624.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7784-13
Recombinant Human Interleukin-17F/IL-17F Protein (His Tag)(Active) 10ug
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89-7784-14
Recombinant Human Interleukin-17F/IL-17F Protein (His Tag)(Active) 50ug
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