89-7783-72 Recombinant Human ITGA5 Protein (His Tag)(Active) 10ug PKSH032600
[Elabscience]
特徴
- 背景：Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection; the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts; endothelial cells; peripheral T cells and platelets. Integrin α-5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains. In addition to adhesion; ITGA5 participates in cell-surface mediated signalling.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P08648
- タグ種類：C-6His
- アミノ酸配列：Phe42-Tyr995
- 遺伝子構造：Recombinant Human Integrin α-5 is produced by our Mammalian expression system and the target gene encoding Phe42-Tyr995 is expressed with a 6His tag at the C-terminus.
- 活性：Immobilized Human NovoNectin(Cat: PKSH032450) at 2μg/ml(100 μl/well) can bind Human ITGA5-His. The ED50 of Human ITGA5-His is 18.9 ug/ml .
- 別名（遺伝子名）：Integrin Alpha-5; CD49 Antigen-Like Family Member E; Fibronectin Receptor Subunit Alpha; Integrin Alpha-F; VLA-5; CD49e; ITGA5; FNRA
- 分子量：105.1 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH 7.2.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106324-Elabscience-PKSH032600.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7783-72
Recombinant Human ITGA5 Protein (His Tag)(Active) 10ug
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89-7783-73
Recombinant Human ITGA5 Protein (His Tag)(Active) 50ug
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