89-7783-63 Recombinant Human IGF-1/IGF1 Protein (aa 52-118)(Active) 50ug PKSH032595
[Elabscience]
特徴
- 背景：Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R; IGF-2R; and the insulin receptor and plays a key role in cell cycle progression; cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 0.5 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P05019
- アミノ酸配列：Thr52-Ala118
- 遺伝子構造：Recombinant Human Insulin-like Growth Factor I is produced by our E.coli expression system and the target gene encoding Thr52-Ala118 is expressed.
- 活性：Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. The ED50 for this effect is 52.4 ng/ml.
- 別名（遺伝子名）：Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1
- 分子量：7.3 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 300mM NaAc; pH 6.5.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106319-Elabscience-PKSH032595.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7783-62
Recombinant Human IGF-1/IGF1 Protein (aa 52-118)(Active) 10ug
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89-7783-63
Recombinant Human IGF-1/IGF1 Protein (aa 52-118)(Active) 50ug
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