89-7783-50 Recombinant Human ITPase/ITPA Protein (His Tag) 10ug PKSH032588
[Elabscience]
特徴
- 背景：Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Defects in ITPase is thought to be inherited and is characterized by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q9BY32
- タグ種類：C-6His
- アミノ酸配列：Ala2-Ala194
- 遺伝子構造：Recombinant Human Inosine Triphosphate Pyrophosphatase is produced by our E.coli expression system and the target gene encoding Ala2-Ala194 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Inosine Triphosphate Pyrophosphatase; ITPase; Inosine Triphosphatase; Non-Canonical Purine NTP Pyrophosphatase; Non-Standard Purine NTP Pyrophosphatase; Nucleoside-Triphosphate Diphosphatase; Nucleoside-Triphosphate Pyrophosphatase; NTPase; Putative Oncogene Protein hlc14-06-p; ITPA; C20orf37
- 分子量：22.5 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, pH 8.0.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106312-Elabscience-PKSH032588.pdf
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89-7783-50
Recombinant Human ITPase/ITPA Protein (His Tag) 10ug
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89-7783-51
Recombinant Human ITPase/ITPA Protein (His Tag) 50ug
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