89-7782-62 Recombinant Human HGF Protein (His Tag)(Active) 50ug PKSH032538
[Elabscience]
特徴
- 背景：Hepatocyte growth factor/scatter factor (HGF/SF) is a paracrine cellular growth, motility and morphogenic factor. It belongs to the peptidase S1 family and Plasminogen subfamily, contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. HGF is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P14210
- タグ種類：C-6His
- アミノ酸配列：Gln32-Ser728
- 遺伝子構造：Recombinant Human Hepatocyte Growth Factor is produced by our Mammalian expression system and the target gene encoding Gln32-Ser728 is expressed with a 6His tag at the C-terminus.
- 活性：Measured by its ability to induce IL-11 secretion by Saos‑2 human osteosarcoma cells. The ED50 for this effect is 0.3-1.5 ng/ml.
- 別名（遺伝子名）：Hepatocyte growth factor;HPTA;HGF;SF;Scatter factor;Hepatopoietin-A
- 分子量：26&53.7&80.7 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106268-Elabscience-PKSH032538.pdf
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89-7782-61
Recombinant Human HGF Protein (His Tag)(Active) 10ug
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89-7782-62
Recombinant Human HGF Protein (His Tag)(Active) 50ug
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