89-7782-37 Recombinant Human RIDA/HRSP12 Protein (His Tag) 10ug PKSH032526
[Elabscience]
特徴
- 背景：Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P52758
- タグ種類：N-6His
- アミノ酸配列：Met 1-Leu137
- 遺伝子構造：Recombinant Human Heat-Responsive Protein 12 is produced by our E.coli expression system and the target gene encoding Met1-Leu137 is expressed with a 6His tag at the N-terminus.
- 別名（遺伝子名）：Ribonuclease UK114; 14.5 kDa Translational Inhibitor Protein; p14.5; Heat-Responsive Protein 12; UK114 Antigen Homolog; HRSP12; PSP
- 分子量：16.7 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106256-Elabscience-PKSH032526.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7782-37
Recombinant Human RIDA/HRSP12 Protein (His Tag) 10ug
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89-7782-38
Recombinant Human RIDA/HRSP12 Protein (His Tag) 50ug
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