89-7782-22 Recombinant Human Haptoglobin/Zonulin Protein (aa 145-406, His Tag) 50ug PKSH032518
[Elabscience]
特徴
- 背景：Haptoglobin(HP) is a secreted protein which is a member of the peptidase S1 family of serine proteases. As a result of hemolysis; hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures; and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin; also known as zonulin; plays a role in intestinal permeability; allowing intercellular tight junction disassembly; and controlling the equilibrium between tolerance and immunity to non-self antigens.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P00738
- タグ種類：N-6His
- アミノ酸配列：Cys145-Asn406
- 遺伝子構造：Recombinant Human Haptoglobin/Zonulin is produced by our E.coli expression system and the target gene encoding Cys145-Asn406 is expressed with a 6His tag at the N-terminus.
- 別名（遺伝子名）：Haptoglobin;Zonulin;HP
- 分子量：31.4 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS;1mM DTT;pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106248-Elabscience-PKSH032518.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7782-22
Recombinant Human Haptoglobin/Zonulin Protein (aa 145-406, His Tag) 50ug
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89-7782-21
Recombinant Human Haptoglobin/Zonulin Protein (aa 145-406, His Tag) 10ug
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