89-7782-19 Recombinant Human Haptoglobin/Zonulin Protein (aa 19-160&aa 162-406, His Tag) 10ug PKSH032517
[Elabscience]
特徴
- 背景：Haptoglobin(HP) is a secreted protein which is a member of the peptidase S1 family of serine proteases. As a result of hemolysis; hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures; and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin; also known as zonulin; plays a role in intestinal permeability; allowing intercellular tight junction disassembly; and controlling the equilibrium between tolerance and immunity to non-self antigens.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P00738
- タグ種類：C-6His
- アミノ酸配列：Val19-Gln160&Ile162-Asn406
- 遺伝子構造：Recombinant Human Haptoglobin/Zonulin is produced by our Mammalian expression system and the target gene encoding Val19-Gln160(alpha chain)&Ile162-Asn406(beta chain) is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Haptoglobin;Zonulin;HP
- 分子量：15.9&28.3
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS; 1mM DTT; pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106247-Elabscience-PKSH032517.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7782-19
Recombinant Human Haptoglobin/Zonulin Protein (aa 19-160&aa 162-406, His Tag) 10ug
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89-7782-20
Recombinant Human Haptoglobin/Zonulin Protein (aa 19-160&aa 162-406, His Tag) 50ug
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