特徴
- 背景:Glia maturation factor beta (GMFB) contains a ADF-H domain,which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.
仕様
- サイズ:50ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:P60983
- タグ種類:C-6His
- アミノ酸配列:Met 1-His142
- 遺伝子構造:Recombinant Human Glia maturation factor beta is produced by our E.coli expression system and the target gene encoding Met1-His142 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Glia maturation factor beta;GMF-beta; GMF
- 分子量:17.7 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 20mM Tris,200mMNaCl,pH8.0.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-106223-Elabscience-PKSH032487.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7781-70
Recombinant Human GMFB Protein (His Tag) 10ug
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89-7781-71
Recombinant Human GMFB Protein (His Tag) 50ug
|
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