89-7781-45 Recombinant Human Galectin-3/LGALS3 Protein (Active) 50ug PKSH032474
[Elabscience]
特徴
- 背景：The Galectin family of proteins consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). They also possess hemagglutination activity; which is attributable to their bivalent carbohydrate binding properties. Galectins are active both intracellularly and extracellularly. They have diverse effects on many cellular functions including adhesion; migration; polarity; chemotaxis; proliferation; apoptosis; and differentiation. Galectins may therefore play a key role in many pathological states; including autoimmune diseases; allergic reactions; inflammation; tumor cell metastasis; atherosclerosis; and diabetic complications. The galectins have been classified into the prototype galectins (1; 2; 5; 7; 10; 11; 13; 14); which contain one CRD and exist either as a monomer or a noncovalent homodimer. The chimera galectins (Galectin3) containing one CRD linked to a nonlectin domain; and the tandem repeat Galectins (4; 6; 8; 9; 12) consisting of two CRDs joined by a linker peptide. Galectins lack a classical signal peptide and can be localized to the cytosolic compartments where they have intracellular functions. However; via one or more as yet unidentified nonclassical secretory pathways; galectins can also be secreted to function extracellularly. Individual members of the galectin family have different tissue distribution profiles and exhibit subtle differences in their carbohydrate-binding specificities. Each family member may preferentially bind to a unique subset of cell surface glycoproteins.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P17931
- アミノ酸配列：Ala2-Ile250
- 遺伝子構造：Recombinant Human Galectin-3 is produced by our E.coli expression system and the target gene encoding Ala2-Ile250 is expressed.
- 活性：Measured by its ability to agglutinate human red blood cells.
- 別名（遺伝子名）：Galectin-3; Gal-3; 35 kDa Lectin; Carbohydrate-Binding Protein 35; CBP35; Galactose-Specific Lectin 3; Galactoside-Binding Protein; GALBP; IgE-Binding Protein; L-31; Laminin-Binding Protein; Lectin L-29; Mac-2 Antigen; LGALS3; MAC2; P35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2
- 分子量：26.0 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; 2mM DTT;pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106210-Elabscience-PKSH032474.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7781-45
Recombinant Human Galectin-3/LGALS3 Protein (Active) 50ug
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89-7781-44
Recombinant Human Galectin-3/LGALS3 Protein (Active) 10ug
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