89-7780-76 ［取扱停止］Recombinant Human FGF-19/FGF9 Protein (His Tag)(Active) 50ug PKSH032436
[Elabscience]
特徴
- 背景：Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile acid absorption. It has been shown to cause resistance to diet-induced obesity and insulin desensitization and to improve insulin, glucose, and lipid profiles in diabetic rodents. FGF19 can be considered as a regulator of energy expenditure.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：O95750
- タグ種類：N-6His
- アミノ酸配列：Phe27-Lys216
- 遺伝子構造：Recombinant Human Fibroblast growth factor 19 is produced by our E.coli expression system and the target gene encoding Phe27-Lys216 is expressed with a 6His tag at the N-terminus.
- 活性：Immobilized Human FGF-19-His at 2μg/ml(100 μl/well) can bind Human FGFR3-Fc(Cat: PKSH033678). The ED50 of Human FGF-19-His is 3.1135 ug/ml.
- 別名（遺伝子名）：Fibroblast growth factor 19; FGF-19; FGF19
- 分子量：23.5 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB，150mM NaCl,pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106177-Elabscience-PKSH032436.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7780-75
Recombinant Human FGF-19/FGF9 Protein (His Tag)(Active) 10ug
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89-7780-76
Recombinant Human FGF-19/FGF9 Protein (His Tag)(Active) 50ug
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