89-7779-65 Recombinant Human Endoglin/CD105 Protein (His&Trx Tag) 50ug PKSH032379
[Elabscience]
特徴
- 背景：Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins and/or other RGD receptors. Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1), which is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P17813-1
- タグ種類：N-Trx
- アミノ酸配列：Glu26-Gln176
- 遺伝子構造：Recombinant Human Endoglin is produced by our E.coli expression system and the target gene encoding Glu26-Gln176 is expressed with a Trx, 6His tag at the N-terminus.
- 別名（遺伝子名）：Endoglin; END; CD105; ENG;HHT1;ORW1
- 分子量：33.6 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM PB，150mM NaCl,pH7.4.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106122-Elabscience-PKSH032379.pdf
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89-7779-64
Recombinant Human Endoglin/CD105 Protein (His&Trx Tag) 10ug
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89-7779-65
Recombinant Human Endoglin/CD105 Protein (His&Trx Tag) 50ug
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