89-7779-32 Recombinant Human DNA Polymerase b/POLB Protein (His Tag) 10ug PKSH032360
[Elabscience]
特徴
- 背景：Human DNA polymerase b is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. It conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. The activity cannot be affected by Aphidicolin, which is an inhibitor of DNA polymerase b.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P06746
- タグ種類：C-6His
- アミノ酸配列：Ser2-Glu335
- 遺伝子構造：Recombinant Human DNA Polymerase beta is produced by our E.coli expression system and the target gene encoding Ser2-Glu335 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：DNA Polymerase Beta; POLB
- 分子量：39.2 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-106106-Elabscience-PKSH032360.pdf
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89-7779-33
Recombinant Human DNA Polymerase b/POLB Protein (His Tag) 50ug
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89-7779-32
Recombinant Human DNA Polymerase b/POLB Protein (His Tag) 10ug
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