特徴
- 背景:Collagen triple helix repeat-containing protein 1 is a protein that in humans is encoded by the CTHRC1 gene. It acts as a negative regulator of collagen matrix deposition. It may cause the disease of Barrett esophagus . Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes.
仕様
- サイズ:50ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:Q96CG8
- タグ種類:C-6His
- アミノ酸配列:Ser31-Lys243
- 遺伝子構造:Recombinant Human Collagen triple helix repeat-containing protein 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Lys243 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Collagen triple helix repeat-containing protein 1;Protein NMTC1;CTHRC1
- 分子量:24.1 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-106042-Elabscience-PKSH032288.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7778-05
Recombinant Human CTHRC1 Protein (His Tag) 10ug
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89-7778-06
Recombinant Human CTHRC1 Protein (His Tag) 50ug
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