89-7777-71 Recombinant Human Complement Component C8 Gamma Chain/C8G Protein (His Tag) 50ug PKSH032271
[Elabscience]特徴
- 背景:Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.
仕様
- サイズ:50ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:P07360
- タグ種類:N-6His
- アミノ酸配列:Gln21-Arg202
- 遺伝子構造:Recombinant Human Complement component C8 gamma chain is produced by our E.coli expression system and the target gene encoding Gln21-Arg202 is expressed with a 6His tag at the N-terminus.
- 別名(遺伝子名):Complement component C8 gamma chain;C8G
- 分子量:22.6 kDa
- 組成:Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-106025-Elabscience-PKSH032271.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
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89-7777-71
Recombinant Human Complement Component C8 Gamma Chain/C8G Protein (His Tag) 50ug
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89-7777-70
Recombinant Human Complement Component C8 Gamma Chain/C8G Protein (His Tag) 10ug
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