89-7776-74 Recombinant Human CD3 epsilon/CD3E Protein (Fc Tag)(Active) 50ug PKSH032212
[Elabscience]特徴
- 背景:T-Cell Surface Glycoprotein CD3 epsilon Chain (CD3epsilon) is a single-pass type I membrane protein. CD3epsilon contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3epsilon is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
仕様
- サイズ:50ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:P07766
- タグ種類:C-Fc
- アミノ酸配列:Asp23-Asp126
- 遺伝子構造:Recombinant Human T-cell surface glycoprotein CD3 epsilon chain is produced by our Mammalian expression system and the target gene encoding Asp23-Asp126 is expressed with a Fc tag at the C-terminus.
- 活性:Immobilized Human CD3E-Fc at 10μg/ml(100 μl/well) can bind Anti-CD3. The ED50 of Human CD3E-Fc is 4.0 ug/ml .
- 別名(遺伝子名):T-Cell Surface Glycoprotein CD3 Epsilon Chain; T-Cell Surface Antigen T3/Leu-4 Epsilon Chain; CD3e; CD3E; T3E;CD3 epsilon;IMD18
- 分子量:38.7 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-105977-Elabscience-PKSH032212.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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89-7776-73
Recombinant Human CD3 epsilon/CD3E Protein (Fc Tag)(Active) 10ug
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89-7776-74
Recombinant Human CD3 epsilon/CD3E Protein (Fc Tag)(Active) 50ug
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