特徴
- 背景:CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64% aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
仕様
- サイズ:50ug
- 種由来:Human
- 発現宿主:Human Cells
- 純度:> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:P32970
- タグ種類:C-Fc
- アミノ酸配列:Gln45-Pro193
- 遺伝子構造:Recombinant Human CD27 Ligand/CD70 is produced by our Mammalian expression system and the target gene encoding Gln45-Pro193 is expressed with a Fc tag at the C-terminus.
- 別名(遺伝子名):CD70 antigen;CD70;CD27 ligand;Tumor necrosis factor ligand superfamily member 7;CD27LG; TNFSF7;CD27L
- 分子量:43.6 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-105974-Elabscience-PKSH032209.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7776-67
Recombinant Human TNFSF7/CD70 Protein (Fc Tag) 10ug
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89-7776-68
Recombinant Human TNFSF7/CD70 Protein (Fc Tag) 50ug
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