特徴
- 背景：C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P51671
- アミノ酸配列：Gly24-Pro97
- 遺伝子構造：Recombinant Human C-C Motif Chemokine 11 is produced by our E.coli expression system and the target gene encoding Gly24-Pro97 is expressed.
- 別名（遺伝子名）：Eotaxin; C-C Motif Chemokine 11; Eosinophil Chemotactic Protein; Small-Inducible Cytokine A11; CCL11; SCYA11
- 分子量：8.6 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl，pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105957-Elabscience-PKSH032186.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7776-34
Recombinant Human CCL11/Eotaxin Protein 50ug
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89-7776-33
Recombinant Human CCL11/Eotaxin Protein 10ug
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