89-7776-10 Recombinant Human Carboxypeptidase B2/CPB2 Protein (His Tag) 50ug PKSH032172
[Elabscience]
特徴
- 背景：Carboxypeptidase B2 (CPB2) is a secreted enzyme that belongs to the peptidase M14 family. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen by the liver and circulates in the plasma as a plasminogen-bound zymogen. CPB2 cleaves C-terminal arginine or lysine residues from biologically active peptides, such as kinins or anaphylatoxins, in the circulation regulating their activities. CPB2 also down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. CPB2 exhibits carboxypeptidase activity when it is activated by proteolysis at residue Arg92 of the thrombin/thrombomodulin complex. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q96IY4
- タグ種類：C-6His
- アミノ酸配列：Phe23-Val423
- 遺伝子構造：Recombinant Human Carboxypeptidase B2 is produced by our Mammalian expression system and the target gene encoding Phe23-Val423 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Carboxypeptidase B2; Carboxypeptidase U; CPU; Plasma Carboxypeptidase B; pCPB; Thrombin-Activable Fibrinolysis Inhibitor; TAFI; CPB2
- 分子量：47.0 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,1mM ZnCl2,10%Glycerol,pH7.5.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105945-Elabscience-PKSH032172.pdf
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89-7776-09
Recombinant Human Carboxypeptidase B2/CPB2 Protein (His Tag) 10ug
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89-7776-10
Recombinant Human Carboxypeptidase B2/CPB2 Protein (His Tag) 50ug
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