89-7775-69 ［取扱停止］Recombinant Human Calnexin/CANX Protein (His Tag) 50ug PKSH032149
[Elabscience]
特徴
- 背景：Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 85 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P27824
- タグ種類：C-6His
- アミノ酸配列：His21-Pro481
- 遺伝子構造：Recombinant Human Calnexin is produced by our Mammalian expression system and the target gene encoding His21-Pro481 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Calnexin; IP90; Major Histocompatibility Complex Class I Antigen-Binding Protein p88; p90; CANX
- 分子量：53.5 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, 2mM CaCl, 10% Glycerol, pH 7.5.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105925-Elabscience-PKSH032149.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7775-68
Recombinant Human Calnexin/CANX Protein (His Tag) 10ug
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89-7775-69
Recombinant Human Calnexin/CANX Protein (His Tag) 50ug
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