89-7775-20 Recombinant Human BMPRIA/ALK-3 Protein (Fc & His Tag) 10ug PKSH032120
[Elabscience]
特徴
- 背景：Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2).
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P36894
- タグ種類：C-Fc-6His
- アミノ酸配列：Gln24-Arg152
- 遺伝子構造：Recombinant Human Bone Morphogenetic Protein Receptor Type IA/Activin Receptor-like Kinase 3 is produced by our Mammalian expression system and the target gene encoding Gln24-Arg152 is expressed with a Fc, 6His tag at the C-terminus.
- 別名（遺伝子名）：Bone Morphogenetic Protein Receptor Type-1A; BMP Type-1A Receptor; BMPR-1A; Activin Receptor-Like Kinase 3; ALK-3; Serine/Threonine-Protein Kinase Receptor R5; SKR5; CD292; BMPR1A; ACVRLK3; ALK3;10q23del
- 分子量：42.1 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105901-Elabscience-PKSH032120.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7775-21
Recombinant Human BMPRIA/ALK-3 Protein (Fc & His Tag) 50ug
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89-7775-20
Recombinant Human BMPRIA/ALK-3 Protein (Fc & His Tag) 10ug
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