特徴
- 背景：Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Deficiency of BPGM increases the affinity of cells for oxygen and result in hemolytic anemia.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P07738
- タグ種類：C-6His
- アミノ酸配列：Ser2-Lys259
- 遺伝子構造：Recombinant Human Bisphosphoglycerate Mutase is produced by our E.coli expression system and the target gene encoding Ser2-Lys259 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Bisphosphoglycerate Mutase; BPGM; 2;3-Bisphosphoglycerate Mutase Erythrocyte; 2;3-Bisphosphoglycerate Synthase; 2;3-Diphosphoglycerate Mutase; DPGM; BPG-Dependent PGAM; BPGM
- 分子量：31.0 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM Tris, 1mM DTT, pH 8.0 .
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105900-Elabscience-PKSH032119.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7775-18
Recombinant Human BPGM Protein (His Tag) 10ug
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89-7775-19
Recombinant Human BPGM Protein (His Tag) 50ug
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