特徴
- 背景:BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:O95816
- タグ種類:N-6His
- アミノ酸配列:Met 1-Asn211
- 遺伝子構造:Recombinant Human BAG Family Molecular Chaperone Regulator 2 is produced by our E.coli expression system and the target gene encoding Met1-Asn211 is expressed with a 6His tag at the N-terminus.
- 別名(遺伝子名):BAG Family Molecular Chaperone Regulator 2; BAG-2; Bcl-2-Associated Athanogene 2; BAG2
- 分子量:25.9 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-105896-Elabscience-PKSH032114.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7775-11
Recombinant Human BAG2 Protein (His Tag) 50ug
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89-7775-10
Recombinant Human BAG2 Protein (His Tag) 10ug
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