特徴
- 背景：Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：O15392
- アミノ酸配列：Met 1-Asp142
- 遺伝子構造：Recombinant Human Baculoviral IAP Repeat-Containing Protein 5 is produced by our E.coli expression system and the target gene encoding Met1-Asp142 is expressed.
- 別名（遺伝子名）：Baculoviral IAP Repeat-Containing Protein 5; Apoptosis Inhibitor 4; Apoptosis Inhibitor Survivin; BIRC5; API4; IAP4
- 分子量：20.4 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 0.1M NaCl, pH 7.5.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105892-Elabscience-PKSH032109.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7775-03
Recombinant Human Survivin/BIRC5 Protein 50ug
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89-7775-02
Recombinant Human Survivin/BIRC5 Protein 10ug
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