特徴
- 背景:ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:Q9H1Y0
- アミノ酸配列:Met 1-Asp275
- 遺伝子構造:Recombinant Human Autophagy Related 5 Homolog is produced by our E.coli expression system and the target gene encoding Met1-Asp275 is expressed.
- 別名(遺伝子名):Autophagy protein 5; APG5-like; Apoptosis-specific protein; APG5L; ASP; ATG5;
- 分子量:32.4 kDa
- 組成:Supplied as a 0.2 μm filtered solution of 20mM Tris,0.2M NaCl,1mM DTT,40%glycerol, pH 8.0 .
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-105886-Elabscience-PKSH032101.pdf
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
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- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7774-90
Recombinant Human ATG5 Protein 50ug
|
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89-7774-89
Recombinant Human ATG5 Protein 10ug
|
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