特徴
- 背景:Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 85 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:Q8WYN0
- タグ種類:N-6His
- アミノ酸配列:Met 1-Val398
- 遺伝子構造:Recombinant Human Autophagy Related 4 Homolog A is produced by our E.coli expression system and the target gene encoding Met1-Val398 is expressed with a 6His tag at the N-terminus.
- 別名(遺伝子名):Cysteine Protease ATG4A; AUT-Like 2 Cysteine Endopeptidase; Autophagin-2; Autophagy-Related Cysteine Endopeptidase 2; Autophagy-Related Protein 4 Homolog A; hAPG4A; ATG4A; APG4A; AUTL2
- 分子量:47.5 kDa
- 組成:Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl,pH7.4.
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-105884-Elabscience-PKSH032099.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7774-86
Recombinant Human ATG4A Protein (His Tag) 50ug
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89-7774-85
Recombinant Human ATG4A Protein (His Tag) 10ug
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