特徴
- 背景：Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation.
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P00966
- タグ種類：N-6His
- アミノ酸配列：Met 1-Lys412
- 遺伝子構造：Recombinant Human Argininosuccinate Synthase is produced by our E.coli expression system and the target gene encoding Met1-Lys412 is expressed with a 6His tag at the N-terminus.
- 別名（遺伝子名）：Argininosuccinate Synthase; Citrulline--Aspartate Ligase; ASS1; ASS
- 分子量：42.8 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 50mM Imidazole, 1mM DTT, 40% Glycerol, pH 7.5.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105877-Elabscience-PKSH032092.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7774-71
Recombinant Human ASS1 Protein (His Tag) 10ug
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89-7774-72
Recombinant Human ASS1 Protein (His Tag) 50ug
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