特徴
- 背景:Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amyloid protein (APP) in vivo and may modulate processing of the β-amyloid precursor protein (APP) and hence formation of β-APP.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:O96018
- タグ種類:C-6His
- アミノ酸配列:Met 1-Leu138
- 遺伝子構造:Recombinant Human Amyloid beta A4 Precursor Protein-Binding Family A Member 3 is produced by our E.coli expression system and the target gene encoding Met1-Leu138 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Amyloid Beta A4 Precursor Protein-Binding Family A Member 3; Adapter protein X11Gamma; Neuron-Specific X11L2 Protein; Neuronal Munc18-1-Interacting Protein 3; Mint-3; APBA3; MINT3; X11L2
- 分子量:15.5 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 20mM PB ,150mM NaCl, pH 7.2.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-105850-Elabscience-PKSH032064.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7774-20
Recombinant Human APBA3 Protein (His Tag) 50ug
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89-7774-19
Recombinant Human APBA3 Protein (His Tag) 10ug
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