89-7773-76 Recombinant Human Activin Receptor 2B/ACVR2B Protein (Fc & His Tag)(Active) 10ug PKSH032041
[Elabscience]
特徴
- 背景：Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily; exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding; type I and II receptors form a stable complex; resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity; and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB; also known as ActRIIB; is a type II receptor containing an extracellular domain (ECD); a transmembrane segment; and a cytoplasmic region that includes the kinase domain. ActRIIB is a receptor for activin A; activin B and inhibin A. Multiple ActRIIB isoforms can also be generated; which bind activin isoforms with different affinities.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q13705
- タグ種類：C-Fc-6His
- アミノ酸配列：Ser19-Thr134
- 遺伝子構造：Recombinant Human Activin Receptor Type 2B is produced by our Mammalian expression system and the target gene encoding Ser19-Thr134 is expressed with a Fc; 6His tag at the C-terminus.
- 活性：Immobilized Human/Mouse/Rat Activin A(Cat: PKSH033807) at 5μg/ml(100 μl/well) can bind Human ACVR2B-His. The ED50 of Human ACVR2B-His is 20.58 ng/ml .
- 別名（遺伝子名）：Activin Receptor Type-2B; Activin Receptor Type IIB; ACTR-IIB; ACVR2B;Bone Morphogenetic Protein Receptor Type-2; BMP Type-2 Receptor; BMPR-3; Bone Morphogenetic Protein Receptor Type II; BMP Type II Receptor
- 分子量：41.3 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB;150mM NaCl;pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105829-Elabscience-PKSH032041.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7773-76
Recombinant Human Activin Receptor 2B/ACVR2B Protein (Fc & His Tag)(Active) 10ug
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89-7773-77
Recombinant Human Activin Receptor 2B/ACVR2B Protein (Fc & His Tag)(Active) 50ug
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