89-7773-72 Recombinant Human Activin RIIA/ACVR2A Protein (Fc & His Tag)(Active) 10ug PKSH032039
[Elabscience]
特徴
- 背景：Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins; composed of a ligand-binding extracellular domain with cysteine-rich region; a transmembrane domain; and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding; resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P27037
- タグ種類：C-Fc-6His
- アミノ酸配列：Ala20-Pro134
- 遺伝子構造：Recombinant Human Activin Receptor Type-2A is produced by our Mammalian expression system and the target gene encoding Ala20-Pro134 is expressed with a Fc; 6His tag at the C-terminus.
- 活性：Immobilized Human INHBC-His(Cat: PKSH032587) at 0.8μg/ml(100 μl/well) can bind Human ACVR2A-Fc-6His. The ED50 of Human ACVR2A-Fc-6His is 6.73 ug/ml.
- 別名（遺伝子名）：Activin Receptor Type-2A; Activin Receptor Type IIA; ACTR-IIA; ACTRIIA; ACVR2A; ACVR2
- 分子量：41.2 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB;150mM NaCl;pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105827-Elabscience-PKSH032039.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7773-72
Recombinant Human Activin RIIA/ACVR2A Protein (Fc & His Tag)(Active) 10ug
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89-7773-73
Recombinant Human Activin RIIA/ACVR2A Protein (Fc & His Tag)(Active) 50ug
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