特徴
- 背景：Medium-Chain Specific Acyl-CoA Dehydrogenase (ACADM) is a mitochondrial fatty acid beta-oxidation that belongs to the acyl-CoA dehydrogenase family. ACADM is a homotetramer enzyme that catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. ACADM is specific for acyl chain lengths of 4 to 16. It is essential for converting these particular fatty acids to energy, especially during fasting periods. Defects in ACADM cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：E.coli
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P11310
- タグ種類：N-6His
- アミノ酸配列：Lys26-Asn421
- 遺伝子構造：Recombinant Human Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial is produced by our E.coli expression system and the target gene encoding Lys26-Asn421 is expressed with a 6His tag at the N-terminus.
- 別名（遺伝子名）：Medium-Chain Specific Acyl-CoA Dehydrogenase Mitochondrial; MCAD; ACADM
- 分子量：45.9 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM Tris, 0.1M NaCl, 20% Glycerol, pH 8.5.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105821-Elabscience-PKSH032032.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7773-60
Recombinant Human ACADM/MCAD Protein (His Tag) 10ug
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89-7773-61
Recombinant Human ACADM/MCAD Protein (His Tag) 50ug
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掲載カタログ情報
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