89-7773-48 Recombinant Human 4-1BB/TNFRSF9 Protein (Fc Tag)(Active) 10ug PKSH032026
[Elabscience]
特徴
- 背景：Tumor necrosis factor receptor superfamily member 9(TNFRSF9); also known as CD137 and 4-1BB; is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells; including endothelial cells; chondrocytes; and cells of the central nervous system. CD137 is also broadly expressed by cells of the human immune system; is broadly expressed by cells of the human immune system; including activated CD8+ and CD4+ T cells; activated natural killer (NK) cells; follicular dendritic cells (FDCs) and monocytes. CD137 has diverse roles in the immune response; the one key function is to promote the survival of both T cells and dendritic cells by binding the cognate ligand CD137L (4-1BBL).
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q07011
- タグ種類：C-Fc
- アミノ酸配列：Leu24-Gln186
- 遺伝子構造：Recombinant Human 4-1BB ligand receptor is produced by our Mammalian expression system and the target gene encoding Leu24-Gln186 is expressed with a Fc tag at the C-terminus.
- 活性：Immobilized Human 4-1BBL-His(Cat: PKSH032023) at 0.03μg/ml(100 μl/well) can bind Human 4-1BB-Fc. The ED50 of Human 4-1BB-Fc is 6.86 ug/ml .
- 別名（遺伝子名）：CD137; ILA; TNFRSF9; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA
- 分子量：44.2 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS; pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105815-Elabscience-PKSH032026.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7773-49
Recombinant Human 4-1BB/TNFRSF9 Protein (Fc Tag)(Active) 50ug
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89-7773-48
Recombinant Human 4-1BB/TNFRSF9 Protein (Fc Tag)(Active) 10ug
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