89-7773-18 Recombinant Human TGFB1/TGF-beta 1 Protein (Active) 10ug PKSH032007
[Elabscience]
特徴
- 背景：Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone; articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions; including the control of cell growth; cell proliferation; cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
仕様
- サイズ：10ug
- 種由来：Human
- 発現宿主：Human Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P01137
- アミノ酸配列：Ala279-Ser390
- 遺伝子構造：Recombinant Human Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed.
- 活性：Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T cells. The ED50 for this effect is 0.04-0.2 ng/ml
- 別名（遺伝子名）：Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB;CED;DPD1;TGF-beta 1
- 分子量：12.8 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 50mM Glycine; 50mM NaCl; pH4.0.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105797-Elabscience-PKSH032007.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7773-18
Recombinant Human TGFB1/TGF-beta 1 Protein (Active) 10ug
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89-7773-19
Recombinant Human TGFB1/TGF-beta 1 Protein (Active) 50ug
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