89-7772-71 [取扱停止]Recombinant Human/Cynomolgus VEGFA/VEGF165 Protein (Active) 20ug PKSH031978
[Elabscience]特徴
- 背景:Vascular endothelial growth factor (VEGF); also known as vascular permeability factor (VPF) and VEGF-A; is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects; including mediating increased vascular permeability; inducing angiogenesis; vasculogenesis and endothelial cell growth; promoting cell migration; inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability; thus it was originally referred to as vascular permeability factor.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
仕様
- サイズ:20ug
- 種由来:Human
- 発現宿主:HEK293 Cells
- 純度:> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per ug as determined by the LAL method.
- アクセッションNo.:P15692-4
- アミノ酸配列:Met 1-Arg191
- 遺伝子構造:A DNA sequence encoding the human VEGF165 isoform (P15692-4) (Met1-Arg191) was expressed. Human and Cynomolgus VEGF165 sequences are identical.
- 活性:Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC).The ED50 for this effect is typically 4-16 ng/mL.
- 別名(遺伝子名):MVCD1;VEGF;VEGF165;VPF;Vascular Endothelial Growth Factor Isoform 165
- 分子量:19.2 kDa
- 組成:Lyophilized from sterile 100 mM Glycine; 10 mM NaCl; pH 7.0.1. Normally 5 % - 8 % trehalose; mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.2. Please contact us for any concerns or special requirements.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-105769-Elabscience-PKSH031978.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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89-7772-72
Recombinant Human/Cynomolgus VEGFA/VEGF165 Protein (Active) 100ug
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89-7772-71
Recombinant Human/Cynomolgus VEGFA/VEGF165 Protein (Active) 20ug
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