89-7772-57 ［取扱停止］Recombinant Human/Mouse/Rat/Cynomolgus/Canine BDNF Protein (Active) 5ug PKSH031967
[Elabscience]
特徴
- 背景：BDNF is a member of the nerve growth factor family. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It functions as the major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
仕様
- サイズ：5ug
- 種由来：Mouse/Human/Rat
- 発現宿主：CHO Stable Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：P21237
- アミノ酸配列：Met 1-Arg249
- 遺伝子構造：A DNA sequence encoding the mouse BDNF (P21237) (Met1-Arg249) was expressed and its mature form was purified. The mature form of human, mouse, rat, cynomolgus and canine BDNF sequences are identical.
- 活性：Measured by its ability to bind biotinylated human TrkB-His in functional ELISA.2. Measured by its ability to bind Human TrkB-Fch in functional ELISA.3. Measured by its ability to bind biotinylated mouse TrkB-His in functional ELISA.
- 別名（遺伝子名）：BDNF
- 分子量：13.5 kDa
- 組成：Lyophilized from sterile PBS
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105762-Elabscience-PKSH031967.pdf
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
|
89-7772-58
Recombinant Human/Mouse/Rat/Cynomolgus/Canine BDNF Protein (Active) 20ug
|
|
|
89-7772-57
Recombinant Human/Mouse/Rat/Cynomolgus/Canine BDNF Protein (Active) 5ug
|
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|