89-7771-79 ［取扱停止］Recombinant Human AgRP/AGRP Protein (Fc Tag) 20ug PKSH031895
[Elabscience]
特徴
- 背景：Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist to proopiomelanocortin (POMC)-derived peptides at the melanocortin-4 receptor (MC4R), and that this homeostatic mechanism is important as a means of coordinating appetite with perceived metabolic requirement. AGRP is upregulated by fasting while intracerebroventricular injections of synthetic AGRP lead to increased appetite and food intake. Thus, AGRP is a powerful orexigenic peptide that increases food intake when ubiquitously overexpressed or when administered centrally.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 97 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_001129.1
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Thr 132
- 遺伝子構造：A DNA sequence encoding the human AgRP (NP_001129.1) (Met 1-Thr 132) was expressed with the fused Fc region of human IgG1 at the C-terminus.
- 別名（遺伝子名）：AGRT;ART;ASIP2
- 分子量：39 kDa
- 組成：Lyophilized from sterile PBS, pH 7.2
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105747-Elabscience-PKSH031895.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7771-79
Recombinant Human AgRP/AGRP Protein (Fc Tag) 20ug
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89-7771-78
Recombinant Human AgRP/AGRP Protein (Fc Tag) 10ug
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