89-7771-32 ［取扱停止］Recombinant Human CD155/PVR Protein (Fc Tag)(Active) 50ug PKSH031869
[Elabscience]
特徴
- 背景：CD155; commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5); is a type I transmembrane single-span glycoprotein; and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV); an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhension; migration and NK-cell killing; and thus efficiently prime cell-mediated tumor-specific immunity.Immune CheckpointImmune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: ICC Antibodies Immune Checkpoint Detection: IP Antibodies Immune Checkpoint Detection: FCM Antibodies Immune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint Targets Co-inhibitory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
仕様
- サイズ：50ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 97 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_006496.3
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Asn 343
- 遺伝子構造：A DNA sequence encoding the extracellular domain (Met 1-Asn 343) of human CD155 (NP_006496.3) was expressed with the C-terminal fused Fc region of human IgG1.
- 活性：Measured by its binding ability in a functional ELISA. Immobilized human DNAM1 at 2 μg/ml (100 μl/well) can bind human CD155-Fc with a linear ranger of 0.032-0.8 μg/ml.
- 別名（遺伝子名）：CD155;HVED;Necl-5;NECL5;PVS;TAGE4
- 分子量：61.8 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105741-Elabscience-PKSH031869.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7771-32
Recombinant Human CD155/PVR Protein (Fc Tag)(Active) 50ug
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89-7771-33
Recombinant Human CD155/PVR Protein (Fc Tag)(Active) 100ug
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