89-7770-97 [取扱停止]Recombinant Human IL36G/IL1F9 Protein (aa 18-169) 10ug PKSH031851
[Elabscience]特徴
- 背景:Junctional adhesion molecules (JAMs) are endothelial and epithelial adhesion molecules involved in the recruitment of circulating leukocytes to inflammatory sites. JAML (Junctional adhesion molecule-like); also known as AMICA1 (Adhesion molecule interacting with CXADR antigen 1); a protein related to the JAM family; is restricted to leukocytes and promotes their adhesion to endothelial cells. It contains 2 extracellular immunoglobulin-like domains; a transmembrane segment; and a cytoplasmic tail involved in activation signaling. Monocytic JAML/AMICA1 plays a critical role in regulating monocyte transendothelial migration (TEM) probably via binding to the endothelial coxsackie and adenovirus receptor (CAR) and other tight junction-associated adhesive molecules. The Expression of JAML/AMICA1 is restricted to the hematopoietic tissues with the exception of liver. JAML may function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes; JAML/AMICA1 also enhances myeloid leukemia cell adhesion to endothelial cells.
仕様
- サイズ:10ug
- 種由来:Human
- 発現宿主:E.coli
- 純度:> 96 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度:Please contact us for more information.
- アクセッションNo.:NP_062564
- アミノ酸配列:Ser18-Asp169
- 遺伝子構造:A DNA sequence encoding the human IL1F9 (NP_062564) (Ser18-Asp169) was expressed and purified; with two additional amino acids (Gly & Pro) at the N-terminus.
- 別名(遺伝子名):Interleukin-36 gamma; IL36G; IL-1-related protein 2; IL-1RP2; IL-1 epsilon; IL-1F9; Interleukin-1 homolog 1; IL-1H1;IL1E;IL1F9;IL1H1;IL1RP2
- 分子量:17 kDa
- 組成:Lyophilized from sterile PBS pH 7.4
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-105736-Elabscience-PKSH031851.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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89-7770-98
Recombinant Human IL36G/IL1F9 Protein (aa 18-169) 20ug
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89-7770-97
Recombinant Human IL36G/IL1F9 Protein (aa 18-169) 10ug
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