89-7769-97 ［取扱停止］Recombinant Human IL-1R8/IL1RAPL1 Protein (Fc Tag)(Active) 20ug PKSH031796
[Elabscience]
特徴
- 背景：Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of interleukin-1 receptor family. The protein structurally comprises three extracellular immunoglobulin domains; which presumably mediate binding of an as yet unidentified ligand; a transmembrane region; and an intracellular domain; which is likely to enable signalling via the NFkB pathway. The means of signalling is almost certain to be identical to that used by the IL1R family and the more distally related Toll protein. L1RAPL1 protein physically interacts via its 150 aa C-terminal domain with neuronal calcium sensor-1 (NCS-1); a protein widely expressed in neurons and the related chromaffin and PC12 cells. IL1RAPL1 is an integral membrane protein responsible for a nonsyndromic form of mental retardation (MR). It is suggested to affect human cognitive ability to some extent; especially the memory and concentration capability.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_055086.1
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Leu 354
- 遺伝子構造：A DNA sequence encoding the human IL1R8 (NP_055086.1) extracellular domain (Met 1-Leu 354) was fused with the Fc region of human IgG1 at the C-terminus.
- 活性：Measured by its ability to bind biotinylated human IL1α in functional ELISA.
- 別名（遺伝子名）：IL1R8;IL1RAPL;MRX10;MRX21;MRX34;OPHN4;TIGIRR-2
- 分子量：65 kDa
- 組成：Lyophilized from sterile PBS; pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38185-Elabscience-PKSH031796.pdf
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89-7769-96
Recombinant Human IL-1R8/IL1RAPL1 Protein (Fc Tag)(Active) 10ug
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89-7769-97
Recombinant Human IL-1R8/IL1RAPL1 Protein (Fc Tag)(Active) 20ug
|
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