89-7769-92 ［取扱停止］Recombinant Human Contactin 4/CNTN4 Protein (His Tag) 20ug PKSH031794
[Elabscience]
特徴
- 背景：Contactin-4, abbreviated as CNTN4, is a brain-derived protein belonging to the immunoglobulin superfamily. It has been found high expression in testes, thyroid, small intestine, uterus and brain. This protein is an neuronal membrane protein that functions as an glycosylphosphatidylinositol- anchored cell adhesion molecule. Contactin-4 is considered as a candidate protein responsible for the differentiation potential of human neuroblastoma cells and it has been implicated in some cases of autism and spinocerebellar ataxia type 16. Studies of the cantactin family have revealed a complex pattern of hemophilic and heterophilic interactions that are required for axon growth and pathfinding. Such studies demonstrate that these essential functions are mediated by the combination and juxtaposition of multiple Ig and FNIII domains. Second, these neuronal adhesion molecules demonstrate highly regulated temporal and spatial expression patterns in the CNS. For this reason, the disruption of the regulatory region of the predominant brain-expressed isoform reasonable would be expected to have significant functional consequences.
仕様
- サイズ：20ug
- 種由来：Human
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 90 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：Q8IWV2-1
- タグ種類：C-His
- アミノ酸配列：Met 1-Ser 1000
- 遺伝子構造：A DNA sequence encoding the mature form of human CNTN4 isoform 1 (Q8IWV2-1) (Met 1-Ser 1000) was fused with a polyhistidine tag at the C-terminus.
- 別名（遺伝子名）：AXCAM;BIG-2
- 分子量：110 kDa
- 組成：Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.5, 10% gly
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-105726-Elabscience-PKSH031794.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7769-93
Recombinant Human Contactin 4/CNTN4 Protein (His Tag) 50ug
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89-7769-92
Recombinant Human Contactin 4/CNTN4 Protein (His Tag) 20ug
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