89-7769-91 Recombinant Human S100A1 Protein (Fc Tag)(Active) 100ug PKSH031793
[Elabscience]
特徴
- 背景：S100A1 is a Ca2+binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells; and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation.This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+ release; inhibition of microtubule assembly; and inhibition of PKC-mediated phosphorylation.. Phosphoglucomutase is a target protein whose activity is antagonistically regulated by S100A1; and recently; S100A1 is also identified as a potent molecular chaperone and a new member of the Hsp70/Hsp90 multichaperone complex. S100A1 displays a tissue-specific expression pattern with highest levels in myocardium and is considered to be an important regulator of cardiac contractility. Accordingly; reduced expression or mutations of S100A1 gene have been implicated in cardiomyopathies.
仕様
- サイズ：100ug
- 種由来：Human
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per ug as determined by the LAL method.
- アクセッションＮｏ．：NP_006262.1
- タグ種類：N-Fc
- アミノ酸配列：Gly 2-Ser94
- 遺伝子構造：A DNA sequence encoding the human S100A1 (NP_006262.1) (Gly 2-Ser94) was expressed with the N-terminal fused Fc region of human IgG1.
- 活性：Measured by its ability to bind biotinylated Human Fc-S100B in functional Elisa.
- 別名（遺伝子名）：S100;S100-alpha;S100A
- 分子量：37.1 kDa
- 組成：Lyophilized from sterile 100mM Glycine; 10mM NaCl; 50mM Tris; pH 7.5
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38183-Elabscience-PKSH031793.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7769-91
Recombinant Human S100A1 Protein (Fc Tag)(Active) 100ug
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89-7769-90
Recombinant Human S100A1 Protein (Fc Tag)(Active) 50ug
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